Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
angina models
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "angina models" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Thromboxane B2 is a biological inactive product and circulating catabolite of thromboxane A2. Thromboxane B2 levels in peripheral venous blood and coronary sinus blood can be used as a diagnostic marker for angina. Thromboxane B2 level in serum is also associated with inhibition of COX-1 activity inhibition in platelets. Thromboxane B2 is a major product of prostaglandin endoperoxide metabolism. Thromboxane B2 produces dose-related decreases in airflow rate, tidal volume and dynamic lung compliance, whilst simultaneously increasing pulmonary airway resistance in dog model. Thromboxane B2 appears to be a naturally occurring bronchoactive metabolite in the bioconversion of arachidonic acid .
Cat. No.: HY-19115
CAS No.: 153192-22-4
Target:
Research Areas:
YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946)-induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris .
Cat. No.: HY-183473
CAS No.: 34535-83-6
Target:
Research Areas:
Fenalcomine hydrochloride is an orally active phenethylamine derivative with antianginal activity. Fenalcomine hydrochloride reduces myocardial oxygen consumption, and increases cardiac output and coronary blood flow. Fenalcomine hydrochloride is suitable for angina models complicated by hypertension, diabetes, and old myocardial infarction. Fenalcomine hydrochloride can be used in studies related to angina pectoris .
Cat. No.: HY-183473A
CAS No.: 34616-39-2
Target:
Research Areas:
Fenalcomine is an orally active phenethylamine derivative with antianginal activity. Fenalcomine reduces myocardial oxygen consumption, and increases cardiac output and coronary blood flow. Fenalcomine is suitable for angina models complicated by hypertension, diabetes, and old myocardial infarction. Fenalcomine can be used in studies related to angina pectoris .
Cat. No.: HY-106468
CAS No.: 66451-06-7
Synonyms: FM-24
Target:
Research Areas:
Bornaprolol (FM-24) is a β-adrenoceptor antagonist. Bornaprolol significantly depresses plasma levels of luteinizing hormone (LH) in orchidectomized rat models. Bornaprolol can be used for cardiovascular diseases like hypertension and angina pectoris research .
Cat. No.: HY-183921
CAS No.: 135100-65-1
Target:
Research Areas:
SQ 32547 is a dihydropyridine calcium channel inhibitor with antihypertensive and anti-ischemic activities. SQ 32547 modulates sarcolemmal voltage-dependent calcium channels to inhibit calcium influx, and exerts direct anti-ischemic activity by suppressing myocardial contracture formation and reducing lactate dehydrogenase (LDH) release. SQ 32547 can be used in research related to hypertension, angina pectoris and neurogenic inflammation .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
