153192-22-4
Chemical Structure
YM-430
- CAS No.: 153192-22-4
- Formula:C29H35N3O8
- Molecular Weight:553.60
IUPAC Name: (S)-3-(4-(((S)-2-hydroxy-3-phenoxypropyl)amino)butyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: HBXMSJLNXYLVTA-HOFKKMOUSA-N
SMILES: O=C(C1=C(C)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC([N+]([O-])=O)=C2)OCCCCNC[C@H](O)COC3=CC=CC=C3
Biological Activity: YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946)-induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris[1].
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YM-430 | YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946)-induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris. | |||||||||||||||||||||
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