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Cat. No.: HY-183473

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Fenalcomine hydrochloride

Fenalcomine hydrochloride is an orally active phenethylamine derivative with antianginal activity. Fenalcomine hydrochloride reduces myocardial oxygen consumption, and increases cardiac output and coronary blood flow. Fenalcomine hydrochloride is suitable for angina models complicated by hypertension, diabetes, and old myocardial infarction. Fenalcomine hydrochloride can be used in studies related to angina pectoris.

For research use only. We do not sell to patients.

CAS No.: 34535-83-6
Formula: C₂₀H₂₈ClNO₂
Molecular Weight:349.89

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Fenalcomine hydrochloride Chemical Structure

CAS No.: 34535-83-6

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Biological Activity
- Description
- In Vivo
Chemical Information
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Biological Activity

Description

In Vivo

Fenalcomine hydrochloride alleviates related symptoms of angina pectoris models; it produces equivalent alleviating effects on angina pectoris models complicated with hypertension, diabetes mellitus and old myocardial infarction, and does not induce abnormal fluctuations in blood routine, liver and kidney function, blood lipid, electrolyte and blood glucose indicators of the test system^[1].
Fenalcomine hydrochloride reduces myocardial oxygen consumption, increases cardiac output and coronary blood flow, exerts no inhibitory effect on myocardial contraction, and does not interfere with the respiratory metabolism of cardiomyocytes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 34535-83-6
Molecular Weight 349.89
Formula C₂₀H₂₈ClNO₂
SMILES

OC(CC)C1=CC=C(C=C1)OCCNC(CC2=CC=CC=C2)C.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Raevsky OA, et al. SLIPPER-2001 -- software for predicting molecular properties on the basis of physicochemical descriptors and structural similarity. Journal of chemical information and computer sciences. 2002;42(3):540-9. [Content Brief]

[2]. Suh CG, et al. Antianginal Effect of Fenalcomine Hydrochloride. Korean Circ J. 1981;11(2):101-107.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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