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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
antischistosomal agent
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "antischistosomal agent" in MCE Product Catalog:
2
Target:
Research Areas:
Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent .
Synonyms: CGP4540
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Amoscanate (cgp4540) is phenyl isothiocyanate in which the hydrogen at the para-position has been replaced by a 4-nitroanilinyl group. Amoscanate is an anti-schistosomal agent. Amoscanate, as an isothiocyanate compound and uncoupler of oxidative phosphorylation, potently injures rodent ependyma .
Cat. No.: HY-151433
CAS No.: 2138480-87-0
Antiparasitic agent-10 (Compound 94) is an anti-parasitic agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .
Cat. No.: HY-172794
CAS No.: 3031757-63-5
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Insecticidal agent 23 (compound 17) has antischistosomal efficacy and low toxicity. Insecticidal agent 23 exhibits potent in vitro activity against adult S. japonicum, with an LC50 (72 h) value of 25.31 μM.
Research Areas:
Hycanthone (Standard) is the analytical standard of Hycanthone. This product is intended for research and analytical applications. Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent .
Research Areas:
Antiparasitic agent-36 is a Schistosoma mansoni-targeting antischistosomal agent that exhibits antischistosomal activity in mice with oral effectiveness, and is a nuclear substituted monoaminophenoxyalkane. Antiparasitic agent-36 can be used for the research of schistosomiasis .
Cat. No.: HY-180337
CAS No.: 15382-63-5
Antiparasitic agent-38 is an orally active antischistosomal agent that effectively clears Schistosoma mansoni infections in mice (single oral LD50=0.8 g/kg) and significantly inhibits S. mansoni infection. Antiparasitic agent-38 can be used for research on schistosomiasis, particularly S. mansoni infection .
Cat. No.: HY-W054427
CAS No.: 70842-04-5
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Ro 13-3978 is an orally active antischistosomal agent. Ro 13-3978 exhibits excellent in vivo antischistosomal activity against juvenile and adult Schistosoma mansoni infections. Ro 13-3978 shows no in vivo activity against E. caproni and F. hepatica. Ro 13-3978 blocks dihydrotestosterone-induced proliferation of androgen-dependent cells. Ro 13-3978 can be used in research related to schistosomiasis .
Cat. No.: HY-N18199
CAS No.: 41755-67-3
Target:
Cat. No.: HY-23317
CAS No.: 102759-19-3
N-Methyl-4-(8-phenoxyoctoxy) aniline (Compound 3568) is an anti-schistosomal agent. N-Methyl-4-(8-phenoxyoctoxy) aniline exhibits definite anti-Schistosoma mansoni activity in mouse models, but has high acute toxicity. N-Methyl-4-(8-phenoxyoctoxy) aniline can be used in studies related to schistosomiasis .
Cat. No.: HY-183434
CAS No.: 21738-41-0
Desoxymansil is an anti-schistosomal agent. In mice, rabbits, dogs and monkeys, Desoxymansil undergoes oxidative metabolism via its isopropylaminomethyl side chain to produce a carboxylic acid metabolite, while this metabolic pathway is absent in rats. In rats, Desoxymansil undergoes α-carbon oxidation of the side chain to form an unstable aminomethanol that decomposes; the intermediate product is reduced to an alcohol metabolite, which is excreted in bile in the form of glucuronide. Desoxymansil can be used for the study of schistosomiasis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
