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Results for "

autolysosomal

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P991381
    JST-TfR09

    PPMX-T003

    		 Transferrin Receptor Reactive Oxygen Species (ROS) Ferroptosis Cancer
    JST‑TfR09 (PPMX‑T003) is a human monoclonal antibody (mAb) targeting transferrin receptor 1 (TfR1/CD71). JST‑TfR09 blocks the binding of transferrin to TfR1, inhibits TfR1 internalization, and suppresses cellular iron uptake. JST‑TfR09 triggers ferritin degradation via activating the autolysosomal system, promotes ROS production and lipid peroxidation, and ultimately induces ferroptosis. JST‑TfR09 exhibits cytotoxicity toward human erythroblasts differentiated from hematopoietic stem cells. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .
    JST-TfR09
  • HY-100985
    IPAG

    		Sigma Receptor Cancer
    IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3 . IPAG induces apoptosis .
    IPAG
  • HY-100985R
    IPAG (Standard)

    		Sigma Receptor Reference Standards Cancer
    IPAG (Standard) is the analytical standard of IPAG (HY-100985). This product is intended for research and analytical applications. IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3 . IPAG induces apoptosis .
    IPAG (Standard)

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