3 Results for "

autolysosomal

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "autolysosomal" in MCE Product Catalog:

Cat. No.: HY-P991381
Synonyms: PPMX-T003; TSP-A18
JST‑TfR09 (PPMX‑T003) is a human monoclonal antibody (mAb) targeting transferrin receptor 1 (TfR1/CD71). JST‑TfR09 blocks the binding of transferrin to TfR1, inhibits TfR1 internalization, and suppresses cellular iron uptake. JST‑TfR09 triggers ferritin degradation via activating the autolysosomal system, promotes ROS production and lipid peroxidation, and ultimately induces ferroptosis. JST‑TfR09 exhibits cytotoxicity toward human erythroblasts differentiated from hematopoietic stem cells. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .
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Cat. No.: HY-100985
CAS No.: 193527-91-2
Purity:  99.84%
Target:  

Sigma Receptor

Research Areas:  

Cancer

IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3 . IPAG induces apoptosis .
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Cat. No.: HY-100985R
CAS No.: 193527-91-2
Research Areas:  

Cancer

IPAG (Standard) is the analytical standard of IPAG (HY-100985). This product is intended for research and analytical applications. IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3 . IPAG induces apoptosis .
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