193527-91-2
193527-91-2
Chemical Structure
IPAG
- CAS No.: 193527-91-2
- Formula:C17H22IN3
- Molecular Weight:395.28
IUPAC Name: 1-((1R,3S,5r,7r)-adamantan-2-yl)-3-(4-iodophenyl)guanidine
InChIKey: UUKPIWYXWLJPJF-KZAAHDRASA-N
SMILES: N=C(NC1=CC=C(I)C=C1)NC2[C@H]3C[C@H](C4)C[C@@H]2C[C@H]4C3
Biological Activity: IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3[1]. IPAG induces apoptosis[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IPAG | 99.84% | IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3. IPAG induces apoptosis. | ||||||||||||||||||||
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IPAG (Standard) | ≥98% | IPAG (Standard) is the analytical standard of IPAG (HY-100985). This product is intended for research and analytical applications. IPAG is a potent sigma-1 receptor antagonist with a pKi of 4.3. IPAG induces apoptosis. | ||||||||||||||||||||
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References
- [1]. James M Brimson, et al. Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression. Sci Rep. 2020 Jun 8;10(1):9251. [Content Brief]
- [2]. Halley M Oyer, et al.Small-Molecule Modulators of Sigma1 and Sigma2/TMEM97 in the Context of Cancer: Foundational Concepts and Emerging Themes. Front Pharmacol. 2019 Oct 21;10:1141. [Content Brief]
Keywords
