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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
clopidogrel
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "clopidogrel" in MCE Product Catalog:
32
32 Publications Verification
Synonyms: clopidogrelum
Target:
Research Areas:
Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
32
32 Publications Verification
Cat. No.: HY-17459
CAS No.: 120202-66-6
Synonyms: (S)-(+)-clopidogrel bisulfate; (S)-(+)-clopidogrel hydrogen sulfate
Target:
Research Areas:
Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation [2]．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
1
1 Cited Publications
Synonyms: CLPM hydrochloride; SR 26334 hydrochloride
Target:
Research Areas:
Clopidogrel carboxylic acid (CLPM) hydrochloride is an inactive metabolite of the widely used antiplatelet medication clopidogrel, which serves as a reference standard for quantitative analysis of clopidogrel metabolism. Clopidogrel carboxylic acid hydrochloride has been shown to represent approximately 85% of circulating clopidogrel, hydrolyzed from the active form by esterases. Clopidogrel carboxylic acid hydrochloride plays a crucial role in assessing the pharmacokinetics and bioavailability of clopidogrel in various clinical and research settings.
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Clopidogrel thiolactone is an important intermediate in the metabolism of Clopidogrel (HY-15283). Clopidogrel thiolactone has antiplatelet aggregatione effects. Clopidogrel is a P2Y12 receptor inhibitor that exerts antiplatelet effects .
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(±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .
Cat. No.: HY-141749A
CAS No.: 144457-28-3
Synonyms: CLPM; SR 26334
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Research Areas:
Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum .
Cat. No.: HY-141749S
CAS No.: 1246814-52-7
Synonyms: (Rac)-CLPM-d4; (Rac)-SR 26334-d4
Synonyms: clopidogrel-MP-AM
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Research Areas:
cis-Clopidogrel-MP derivative (Clopidogrel-MP-AM) is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite . Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor .
Cat. No.: HY-W011114
CAS No.: 144750-52-7
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Clopidogrel-related Compound B hydrochloride is an impurity of Clopidogrel (HY-15283).
Synonyms: (±)-SR-121683
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(±)-2-Oxo clopidogrel is a metabolite of the antiplatelet agent Clopidogrel (HY-15283) .
Cat. No.: HY-143817S
CAS No.: 2140305-74-2
Synonyms: clopidogrelum-d3 hydrochloride
Cat. No.: HY-W778270
CAS No.: 1794713-84-0
Cat. No.: HY-150528S
CAS No.: 1219423-91-2
Cat. No.: HY-Z2483S
CAS No.: 1346597-76-9
Cat. No.: HY-111755
CAS No.: 2299200-91-0
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P2Y12 antagonist 2 is a potent P2Y12 receptor antagonist. P2Y12 antagonist 2 exhibits excellent antiplatelet aggregation potency with an IC50 value of 2.94 μM as well as antithrombotic efficacy in a rat ferric chloride model. P2Y12 antagonist 2 shows a superior safety profile than Clopidogrel (HY-15283) in a rat tail-bleeding model. P2Y12 antagonist 2 can be used to research thromboembolic disorders .
Cat. No.: HY-120612
CAS No.: 1557206-59-3
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Research Areas:
BMS-884775 is a selective and orally active P2Y1 antagonist with an IC50 of 0.1 nM for the human P2Y1 receptor. BMS-884775 has a similar efficacy in preventing arterial thrombosis to Clopidogrel (HY-15283) and Prasugrel (HY-15284), but treatment with BMS-884775 results in shorter bleeding time and lower bleeding risk. BMS-884775 can be used in research related to antiplatelet and arterial thrombosis-associated diseases .
Cat. No.: HY-17459R
CAS No.: 120202-66-6
Synonyms: (S)-(+)-clopidogrel bisulfate (Standard); (S)-(+)-clopidogrel hydrogen sulfate (Standard)
Research Areas:
Clopidogrel (hydrogen sulfate) (Standard) is the analytical standard of Clopidogrel (hydrogen sulfate). This product is intended for research and analytical applications. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation [2]．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
Cat. No.: HY-17459S
CAS No.: 1217643-68-9
Synonyms: (S)-(+)-clopidogrel bisulfate-d3; (S)-(+)-clopidogrel-d3 hydrogen sulfate
Cat. No.: HY-110043
CAS No.: 130209-90-4
Target:
Research Areas:
(±)-Clopidogrel hydrochloride is an antithrombotic agent that is ADP-selective and orally available. (±)-Clopidogrel hydrochloride inhibits platelet aggregation by inhibiting the binding of ADP to its platelet receptors .
Cat. No.: HY-15283R
CAS No.: 113665-84-2
Synonyms: clopidogrelum (Standard)
Target:
Research Areas:
Clopidogrel (Standard) is the analytical standard of Clopidogrel. This product is intended for research and analytical applications. Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
