2 Results for "

dendrite retraction

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "dendrite retraction" in MCE Product Catalog:

2
Methylophiopogonanone B
Methylophiopogonanone B
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2 Cited Publications
Cat. No.: HY-N2438
CAS No.: 74805-91-7
Category:  

Ophiopogon japonicus (L. f.) Ker-Gawl. Liliaceae Flavonoids Other Diseases Phenols Polyphenols Plants Disease Research Fields Other Flavonoids

Target:  

Ras Microtubule/Tubulin

Methylophiopogonanone B is a homoisoflavonoid compound. Methylophiopogonanone B can be isolated from O. japonicus root. Methylophiopogonanone B promotes Rho activation and Tubulin depolymerization. Methylophiopogonanone B significantly increases GTP-Rho, but not GTP-Rac or GTP-CDC42. Methylophiopogonanone B induces cell morphological change via melanocyte dendrite retraction and stress fiber formation. Methylophiopogonanone B exhibits strong antioxidant activity. Methylophiopogonanone B can be used in the research of cervical cancer .
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Centaureidin
Centaureidin
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Cat. No.: HY-N10341
CAS No.: 17313-52-9
Category:  

Flavonoids Flavones Angelica lucida L. Plants Compositae

Target:  

IFNAR ROCK

Centaureidin is an orally active IFN-promoter that can be isolated from Bidens pilosa with an EC50 of 0.9 μg/mL. Centaureidin activates the Rho signal pathway, leading to actin and tubulin disassembly, and resulting in dendrite retraction and stress fiber formation in melanocytes. Centaureidin shows high tumor cell growth inhibitory activities. Centaureidin significantly inhibits paw edema in mice [1][2][3][4][5].
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