8 Results for "

deuterated version

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "deuterated version" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0100S
CAS No.: 1192260-78-8
Naringenin-d4 is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity .
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Cat. No.: HY-145119AS
CAS No.: 2779498-79-0
Purity:  99.46%
Synonyms: VV116; GS-621763-d1 hydrobromide
Mindeudesivir (JT001; VV116; GS-621763-d1) hydrobromide is a deuterated version of Remdesivir (HY-104077), a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19 .
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Cat. No.: HY-12678S1
CAS No.: 2251773-94-9
Purity:  99.82%
Synonyms: NMS-E628-d8; RXDX-101-d8
Entrectinib-d8 (NMS-E628-d8; RXDX-101-d8) is a deuterated version of Entrectinib (HY-12678). Entrectinib (NMS-E628) is an orally available, blood-brain barrier permeable, central nervous system active TrkA/B/C, ROS1 and ALK inhibitor with IC50 values of 1, 3, 5, 12 and 12, respectively. 7 nM. Entrectinib induces apoptosis and cycle arrest in cancer cells, has anti-tumor activity, and also alleviates bleomycin-induced pulmonary fibrosis in mice .
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Cat. No.: HY-15414S
CAS No.: 2140316-62-5
Synonyms: Lu AA 21004 d8
Vortioxetine-d8 (Lu AA 21004-d8) is a deuterated version of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM) .
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Cat. No.: HY-100441S3
Synonyms: UT-15-d7
Treprostinil-d7 (UT-15-d7) is a deuterated version of Treprostinil (HY-100441). Treprostinil is a highly potent DP1 and EP2 agonist with EC50s of 0.6 nM and 6.2 nM, respectively .
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Cat. No.: HY-10493S
CAS No.: 2699607-48-0
Synonyms: GS-9350-d8
Cobicistat-d8 (GS-9350-d8) is a deuterated version of Cobicistat (HY-10493). Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) with IC50 values of 30-285 nM. Cobicistat is a pharmacokinetic enhancer that enhances the absorption of anti-HIV active molecules .
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Cat. No.: HY-32067AS
CAS No.: 2713384-81-5
Aceclidine-d3 hydrochloride is a deuterated version of Aceclidine (HY-32067). Aceclidine is a modulator of the M3 muscarinic acetylcholine receptor.
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Cat. No.: HY-W004286S
CAS No.: 96731-86-1
Synonyms: Methyl dodecanoate-d3
Methyl laurate-d3 is the deuterated Methyl laurate. Methyl laurate, a 12-carbon saturated fatty acid, is an esterified version of lauric acid.
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