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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
endocytic vesicles
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "endocytic vesicles" in MCE Product Catalog:
Cat. No.: HY-D3383
Target:
Research Areas:
AM4-64 is a fixable cationic styryl fluorescent dye for nerve terminals, which can be used for vesicle cycle evaluation, endocytic pathway tracing and endocytosis detection. AM4-64 inserts into the plasma membrane, is internalized via activity- or energy-dependent endocytosis, and accumulates in vesicles, endosomal compartments, vacuolar membranes, mitochondria and endolysosomal structures. The fluorescence of AM4-64 is enhanced in the membrane-bound state. AM4-64 is applicable to relevant studies on neurons, plant and fungal cells and tissues (Ex/Em = 510/750 nm) .
Cat. No.: HY-D3197
Cat. No.: HY-L072
56 compounds
Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.
The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 56 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.
Cat. No.: HY-D3423
Synonyms: FM 2-10FX
Target:
Research Areas:
AM2-10 (FM 2-10FX) is a Fluorescent dye used for liquid-phase endocytosis imaging. AM2-10 stains cell membranes to observe neurite length during NGF-induced cell differentiation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
