1 Result for "

gp130 homodimerization

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "gp130 homodimerization" in MCE Product Catalog:

Cat. No.: HY-N14323
CAS No.: 184877-64-3
Madindoline A is an orally active gp130 antagonist with a KD of 288 μM. Madindoline A inhibits IL-6- and IL-11-induced osteoclastogenesis, suppresses IL-6-stimulated serum amyloid A protein production, inhibits bone resorption and bone loss, and also inhibits IL-6- and IL-11-dependent cell line growth, as well as IL-6-dependent Stat3 tyrosine phosphorylation. Madindoline A is applicable for the research of hormone-dependent postmenopausal osteoporosis .
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