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Results for "

h-NTPDase1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-143288
    NTPDase-IN-2

    		NTPDase Infection Inflammation/Immunology Cancer
    NTPDase-IN-2 (compound 5g) is a selective NTPDase inhibitor with IC50s of 0.04 and 2.27 µM for h-NTPDase-2/-8, respectively. NTPDase-IN-2 non-competitively inhibits h-NTPDase-1/-2 with a Km of 74 µM for h-NTPDase-2. NTPDase-IN-2 can be used in studies of cancer, immunologic disorders as well as bacterial infections [1].
    NTPDase-IN-2
  • HY-143287
    NTPDase-IN-1

    		NTPDase Infection Inflammation/Immunology Cancer
    NTPDase-IN-1 (compound 5a) is a selective NTPDase inhibitor with IC50s of 0.05, 0.23 and 0.54 µM for h-NTPDase-1/-2/-8, respectively. NTPDase-IN-1 non-competitively inhibits h-NTPDase-1/-2 with a Km of 21 µM for h-NTPDase-1. NTPDase-IN-1 can be used in studies of cancer, immunologic disorders as well as bacterial infections [1].
    NTPDase-IN-1
  • HY-155596
    h-NTPDase-IN-1

    		NTPDase Cancer
    h-NTPDase-IN-1 (Compound 3i) is a h-NTPDase inhibitor (IC50: 2.88 μM and 0.72 μM for h-NTPDase1 and h-NTPDase3 respectively). h-NTPDase-IN-1 can be used for research of thrombosis, inflammation, diabetes, and cancer [1].
    h-NTPDase-IN-1
  • HY-155828
    h-NTPDase-IN-4

    		NTPDase Cancer
    h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
    h-NTPDase-IN-4
  • HY-155829
    h-NTPDase-IN-5

    		NTPDase Others
    h-NTPDase-IN-5 (compound 3b) is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8).
    h-NTPDase-IN-5
  • HY-155827
    h-NTPDase-IN-3

    		NTPDase Others
    h-NTPDase-IN-3 (compound 4d) is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).
    h-NTPDase-IN-3
  • HY-155806
    h-NTPDase-IN-2

    		Phosphatase Others
    h-NTPDase-IN-2 (compound 3l) is a pan-inhibitor of h-NTPDase, with IC50s of 0.35 μM (h-NTPDase1), 4.81 μM (h-NTPDase2), 37.73 μM (h-NTPDase3), 10.32 μM (h-NTPDase8), respectively [1].
    h-NTPDase-IN-2
  • HY-181981
    NTPDase/NPP1-IN-1

    		NTPDase Phosphodiesterase (PDE) Cancer
    NTPDase/NPP1-IN-1 is an ectonucleotidase (NTPDase) and nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) inhibitor, with IC50 values of 0.28, 0.92, 0.82 and 0.73 μM against h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NPP1, respectively. NTPDase/NPP1-IN-1 is a membrane-interacting agent that localizes to the plasma membrane and interacts with cancer cells. NTPDase/NPP1-IN-1 can be used in the research of breast cancer [1].
    NTPDase/NPP1-IN-1

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