h-NTPDase-IN-4
Based on 1 Customer Validation
h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
For research use only. We do not sell to patients.
- Purity: 98.64%
- CAS No.: 2939933-09-0
- Formula: C22H8F12N2S
- Molecular Weight:560.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8)
Chemical Information
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CAS No. 2939933-09-0
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Appearance Solid
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Molecular Weight 560.36
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Formula C22H8F12N2S
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Color White to off-white
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SMILES
FC(C1=CC(C2=NC=NC3=C2SC=C3C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=CC(C(F)(F)F)=C1)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : 100 mg/mL (178.46 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 1.7846 mL | 8.9228 mL | 17.8457 mL | 44.6142 mL |
| 5 mM | 0.3569 mL | 1.7846 mL | 3.5691 mL | 8.9228 mL | |
| 10 mM | 0.1785 mL | 0.8923 mL | 1.7846 mL | 4.4614 mL | |
| 15 mM | 0.1190 mL | 0.5949 mL | 1.1897 mL | 2.9743 mL | |
| 20 mM | 0.0892 mL | 0.4461 mL | 0.8923 mL | 2.2307 mL | |
| 25 mM | 0.0714 mL | 0.3569 mL | 0.7138 mL | 1.7846 mL | |
| 30 mM | 0.0595 mL | 0.2974 mL | 0.5949 mL | 1.4871 mL | |
| 40 mM | 0.0446 mL | 0.2231 mL | 0.4461 mL | 1.1154 mL | |
| 50 mM | 0.0357 mL | 0.1785 mL | 0.3569 mL | 0.8923 mL | |
| 60 mM | 0.0297 mL | 0.1487 mL | 0.2974 mL | 0.7436 mL | |
| 80 mM | 0.0223 mL | 0.1115 mL | 0.2231 mL | 0.5577 mL | |
| 100 mM | 0.0178 mL | 0.0892 mL | 0.1785 mL | 0.4461 mL |