2326978-03-2
2326978-03-2
Chemical Structure
NTPDase/NPP1-IN-1
- CAS No.: 2326978-03-2
- Formula:C16H10F2N2O
- Molecular Weight:284.26
InChIKey: VYESMFOCSQTSOF-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2N=CC=CC2=C1)NC3=C(F)C=CC=C3F
Biological Activity: NTPDase/NPP1-IN-1 is an ectonucleotidase (NTPDase) and nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) inhibitor, with IC50 values of 0.28, 0.92, 0.82 and 0.73 μM against h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NPP1, respectively. NTPDase/NPP1-IN-1 is a membrane-interacting agent that localizes to the plasma membrane and interacts with cancer cells. NTPDase/NPP1-IN-1 can be used in the research of breast cancer[1].
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NTPDase/NPP1-IN-1 | NTPDase/NPP1-IN-1 is an ectonucleotidase (NTPDase) and nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) inhibitor, with IC50 values of 0.28, 0.92, 0.82 and 0.73 μM against h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NPP1, respectively. NTPDase/NPP1-IN-1 is a membrane-interacting agent that localizes to the plasma membrane and interacts with cancer cells. NTPDase/NPP1-IN-1 can be used in the research of breast cancer. | |||||||||||||||||||||
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