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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
289 Results for "
information
" in MedChemExpress (MCE) Product Catalog:
Products (289)
289 Results for "information" in MCE Product Catalog:
Art. -Nr.: HY-P2847
CAS. Nr.: 330648-32-3
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Synonyms: C6-HSL
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N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis .
Art. -Nr.: HY-137989A
Reinheit: 99.52%
Synonyms: Voriconazole oxynitride hydrochloride
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Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200) , a widely used triazole antibiotic (fungal). Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity .
SIRT1-IN-2 (compound 3h) is a potent and selective SIRT1 (silent information regulator 1) inhibitor, with an IC50 of 1.6 μM .
Synonyms: INCB54707 phosphate
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Povorcitinib (INCB54707) phosphate is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib phosphate can be used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) (information extracted from patent WO2021076124A1) .
Art. -Nr.: HY-132138A
Reinheit: 98.02%
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5-Propargylamino-3'-azidomethyl-dCTP (TEA) is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 17 in patent document WO2004018497A2. 5-Propargylamino-3'-azidomethyl-dCTP (TEA) is a click chemistry reagent containing an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC) .
Art. -Nr.: HY-133685R
CAS. Nr.: 147852-83-3
Synonyms: C6-HSL (Standard)
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Forschungsgebiete:
N-Hexanoyl-L-homoserine lactone (Standard) is the analytical standard of N-Hexanoyl-L-homoserine lactone (HY-133685). This product is intended for research and analytical applications. N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis.
Art. -Nr.: HY-14843
CAS. Nr.: 610300-07-7
Synonyms: PD-0332334free base
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Imagabalin (PD-0332334 free base) is an active compound with activity for studying neurological diseases. The synthesis of imagabalin involves the reaction of 3-methylvaleric acid and Meldrum acid. During the synthesis of imagabalin, an acyl chloride intermediate species, 3-methylvaleryl chloride, was revealed for the first time. The synthesis of imagabalin also provided new information about the reaction mechanism, indicating that 3-methylvaleric anhydride is an important intermediate .
Art. -Nr.: HY-113218S
CAS. Nr.: 203805-90-7
Synonyms: O-Acetyl-L-carnitine-d9; ALCAR-d9
Art. -Nr.: HY-W131302
CAS. Nr.: 5657-17-0
Synonyms: N,N-Ethylenediglycine
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Ethylenediaminediacetic acid (N,N-Ethylenediglycine) is an important ligand that enhances the antiproliferative activity of metal complexes. The complexes formed by ethylenediacetic acid and metal ions exhibited significant antiproliferative properties in MCF-7 cancer cell line. The metal complexes of ethylenediacetic acid were able to interact with DNA and were studied by CD and EPR spectroscopy techniques. Ethylenediaminediacetic acid and its metal complexes were able to induce cell cycle arrest at the G(0)/G(1) phase. The crystal structure analysis of ethylenediacetic acid provided important structural information for understanding its biological activity .
Art. -Nr.: HY-P5158
CAS. Nr.: 381725-58-2
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Art. -Nr.: HY-117747
CAS. Nr.: 151867-81-1
Synonyms: JCR 424; XM 323
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DMP 323 is a potent, nonpeptide cyclic urea inhibitor of HIV protease, effective against both HIV type 1 and type 2. Designed using structural information and database searching, it competitively inhibits the cleavage of both peptide and HIV-1 gag polyprotein substrates. DMP 323 shows comparable potency to other highly effective HIV protease inhibitors like A-80987 and Ro-31-8959. Importantly, its efficacy against HIV protease remains unaffected by human plasma or serum, suggesting low affinity for plasma proteins. Furthermore, DMP 323 demonstrates minimal inhibition of various mammalian proteases at concentrations much higher than those needed for HIV protease inhibition, highlighting its specificity for viral targets .
Art. -Nr.: HY-123444
CAS. Nr.: 129297-22-9
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Kijimicin is a polyether antibiotic, and its specific mechanism of activity and application details are not described in detail from the existing information.
Art. -Nr.: HY-164556
CAS. Nr.: 17434-81-0
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3′-Deoxy-5′-AMPIt can be used to study various physiological processes such as energy metabolism and information transmission.
Art. -Nr.: HY-164556A
CAS. Nr.: 71997-30-3
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3′-Deoxy-5′-AMP sodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.
Art. -Nr.: HY-138227
CAS. Nr.: 13052-95-4
Synonyms: 3′-dADP
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3′-Deoxyadenosine 5′-diphosphate (3′-dADP)It can be used to study various physiological processes such as energy metabolism and information transmission.
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Art. -Nr.: HY-138227A
CAS. Nr.: 71997-31-4
Synonyms: 3′-dADP disodium
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3′-Deoxyadenosine 5′-diphosphate (3′-dADP) disodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.
Art. -Nr.: HY-19407
CAS. Nr.: 471854-50-9
Nor-LY-510929 is a compound whose development in the field of endocrinology and metabolism was stopped in 2005. Its specific active mechanism and application details are not described in detail based on the existing information.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
