1637677-33-8
Chemical Structure
Povorcitinib phosphate
Synonym(s): INCB54707 phosphate
- CAS 番号: 1637677-33-8
- Formula:C23H25F5N7O5P
- Molecular Weight:605.45
IUPAC Name: (S)-4-(3-(cyanomethyl)-3-(3',5'-dimethyl-1H,1'H-[4,4'-bipyrazol]-1-yl)azetidin-1-yl)-2,5-difluoro-N-(1,1,1-trifluoropropan-2-yl)benzamide phosphate
InChIKey: XUQIWHXYCLHHCN-UQKRIMTDSA-N
SMILES: O=P(O)(O)O.N#CCC1(N2C=C(C3=C(C)NN=C3C)C=N2)CN(C4=C(C=C(C(F)=C4)C(N[C@@H](C)C(F)(F)F)=O)F)C1
Biological Activity: Povorcitinib (INCB54707) phosphate is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib phosphate can be used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) (information extracted from patent WO2021076124A1)[1].
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Povorcitinib phosphate | 98.82% | Povorcitinib (INCB54707) phosphate is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib phosphate can be used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) (information extracted from patent WO2021076124A1). | ||||||||||||||||||||
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