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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
mRNA reading frame
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "mRNA reading frame" in MCE Product Catalog:
Synonyms: SRP-4053
Target:
Research Areas:
Golodirsen (SRP-4053) is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen can restore the expression of the anti-myostatin protein. Golodirsen can be used for the research of duchenne muscular dystrophy (DMD) .
Cat. No.: HY-132586
CAS No.: 2055732-84-6
Synonyms: NS-065/NCNP-01
Research Areas:
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .
Synonyms: Kyndrisa; GSK2402968A; PRO051
Target:
Research Areas:
Drisapersen (Kyndrisa) is a 2 '-O-methyl phosphorothioate RNA antisense oligonucleotide that induces exon 51 skipping. Drisapersen induces skipping of exon 51 during Dystrophin pre-mRNA splicing, allowing the synthesis of partially functional Dystrophin. Drisapersen can be used in research related to Duchenne muscular dystrophy .
Cat. No.: HY-132611A
Purity: 92.00%
Synonyms: SRP-4053 sodium
Target:
Research Areas:
Golodirsen (SRP-4053) sodium is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen sodium restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen sodium can restore the expression of the anti-myostatin protein. Golodirsen sodium can be used for the research of duchenne muscular dystrophy (DMD) .
Cat. No.: HY-132586A
Purity: 95.25%
Synonyms: NS-065/NCNP-01 sodium
Research Areas:
Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .
Cat. No.: HY-132584A
Purity: 99.07%
Synonyms: SRP-4045 sodium
Target:
Research Areas:
Casimersen (SRP-4045) sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .
Cat. No.: HY-132584
CAS No.: 1422958-19-7
Synonyms: SRP-4045
Target:
Research Areas:
Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .
Cat. No.: HY-P703303
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SMG6; Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans); Prev. C17orf31; Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor; EST1A; SMG6, Nonsense Mediated mRNA Decay Factor; KIAA0732; Chromosome 17 Open reading frame 31; SMG-6; EST1 Telomer
Cat. No.: HY-P75465
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MRTO4; MRT4, mRNA Turnover 4, Homolog (S. Cerevisiae); Prev. C1orf33; Chromosome 1 Open reading frame 33; MRT4; MRTO4 Ribosome Maturation Factor; DJ657E11.4; 60S Acidic Ribosomal Protein PO; mRNA Turnover Protein 4 Homolog; MRT4, mRNA Turnover 4, Homolog
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
