2 Results for "

oncogenesis

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "oncogenesis" in MCE Product Catalog:

Cat. No.: HY-15241
CAS No.: 902156-99-4
Purity:  98.81%
Synonyms: LCQ-195; AT9311
Target:  

CDK

Research Areas:  

Cancer

NVP-LCQ195 (LCQ-195) is an inhibitor of CDK1/2/3/5/9. NVP-LCQ195 induces cell cycle arrest and eventual apoptotic cell death of multiple myeloma (MM) cells. NVP-LCQ195 triggers decreased amplitude of transcriptional signatures related to oncogenesis, drug resistance and stem cell renewal in MM cell lines .
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Cat. No.: HY-162148
CAS No.: 1980848-48-3
Target:  

EGFR

Research Areas:  

Cancer

HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis .
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