902156-99-4
902156-99-4
Chemical Structure
NVP-LCQ195
Synonym(s): LCQ-195; AT9311
- CAS No.: 902156-99-4
- Formula:C17H19Cl2N5O4S
- Molecular Weight:460.33
IUPAC Name: 4-(2,6-dichlorobenzamido)-N-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazole-5-carboxamide
InChIKey: CCUXEBOOTMDSAM-UHFFFAOYSA-N
SMILES: CS(=O)(N1CCC(NC(C2=C(NC(C3=C(Cl)C=CC=C3Cl)=O)C=NN2)=O)CC1)=O
Biological Activity: NVP-LCQ195 (LCQ-195) is an inhibitor of CDK1/2/3/5/9. NVP-LCQ195 induces cell cycle arrest and eventual apoptotic cell death of multiple myeloma (MM) cells. NVP-LCQ195 triggers decreased amplitude of transcriptional signatures related to oncogenesis, drug resistance and stem cell renewal in MM cell lines[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NVP-LCQ195 | 98.88% | NVP-LCQ195 (LCQ-195) is an inhibitor of CDK1/2/3/5/9. NVP-LCQ195 induces cell cycle arrest and eventual apoptotic cell death of multiple myeloma (MM) cells. NVP-LCQ195 triggers decreased amplitude of transcriptional signatures related to oncogenesis, drug resistance and stem cell renewal in MM cell lines. | ||||||||||||||||||||
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