1980848-48-3
1980848-48-3
Chemical Structure
HNPMI
- CAS No.: 1980848-48-3
- Formula:C22H20N2O3
- Molecular Weight:360.41
InChIKey: IKCOFVYDHULPDI-UHFFFAOYSA-N
SMILES: CC1=CC=C(C(N2CCC3=C2C=CC=C3)C4=CC([N+]([O-])=O)=CC=C4O)C=C1
Biological Activity: HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HNPMI | 99.57% | HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis. | ||||||||||||||||||||
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References
Keywords
