5 Results for "

pKal

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "pKal" in MCE Product Catalog:

Cat. No.: HY-P99110
CAS No.: 1426055-14-2
Synonyms: SHP643; DX-2930; X124-G01

Target:  

Kallikrein

Research Areas:  

Inflammation/Immunology

Lanadelumab (SHP643) is a human IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal. Lanadelumab has the potential for the research of hereditary angioedema .
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Cat. No.: HY-145568
CAS No.: 2166320-76-7
Purity:  99.87%
Synonyms: KVD-824
Target:  

Kallikrein

Feniralstat (compound 30), a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM) .
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Cat. No.: HY-143476
Target:  

Kallikrein

Plasma kallikrein-IN-2 (Compound 198) is a potent plasma kallikrein (PKal) inhibitor with an IC50 of 0.1 nM. Plasma kallikrein-IN-2 can be used for hereditary angioedema, diabetic macular edema, and diabetic retinopathy research .
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Cat. No.: HY-145568A
CAS No.: 2340299-00-3
Target:  

Kallikrein

Feniralstat (compound 30) hydrochloride, a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM) .
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Cat. No.: HY-181798
CAS No.: 2773609-90-6
Target:  

Kallikrein

Research Areas:  

Metabolic Disease

pKal-IN-1 (compound 13) is a plasma kallikrein (pKal) inhibitor. pKal-IN-1 can be used for the research of diabetic macular edema, diabetic retinopathy .
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