2. Immunology/Inflammation
  3. Kallikrein
  4. Feniralstat hydrochloride

Feniralstat (compound 30) hydrochloride, a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM).

For research use only. We do not sell to patients.

Feniralstat hydrochloride

Feniralstat hydrochloride Chemical Structure

CAS No. : 2340299-00-3

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Feniralstat hydrochloride Related Antibodies

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KLK1 KLK5 KLK8 KLK14 KLKB1 KLK10

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Description

Feniralstat (compound 30) hydrochloride, a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM)[1].

Molecular Weight

545.97

Formula

C26H26ClF2N5O4
CAS No.
SMILES

O=C1C=CC(F)=CN1CC2=CC=C(CN3N=C(COC)C(C(NCC4=NC=CC(OC)=C4F)=O)=C3)C=C2.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Feniralstat hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Feniralstat2340299-00-3KallikreinKLKKallikrein-related peptidaseInhibitorinhibitorinhibit

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