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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
125 Results for "
pgf2
" in MedChemExpress (MCE) Product Catalog:
Products (125)
125 Results for "pgf2" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: Prostaglandin F2α; pgf2α
10
10 Publications Verification
Synonyms: Prostaglandin F2α tromethamine salt; pgf2α THAM; Prostaglandin F2α THAM
2
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Ebopiprant (OBE022) is an oral and selective prostaglandin F2α (PGF2α) receptor antagonist, with Kis of 1 nM, 26 nM for human and rat FP receptors, respectively.
2
2 Cited Publications
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AL-8810 is a potent and selective antagonist of the PGF 2α receptor (FP receptor). AL-8810 is an activator of MAPK and ERK1/2. The Ki of the FP receptor of mouse 3T3 cells and rat A7r5 cells are 0.2±0.06 μM and 0.4±0.1 μM, respectively. AL-8810 can be used in the study of elevated intraocular pressure (OHT) and primary open-angle glaucoma (POAG) [2] .
Synonyms: ICI 80996 sodium salt
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Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent , and is a PGF2α receptor agonist [2].
Cat. No.: HY-12956S
CAS No.: 34210-11-2
Synonyms: Prostaglandin F2a-d4; pgf2α-d4
Synonyms: 15(S)-15-Methyl Prostaglandin F2α; 15-Methyl-pgf2α
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Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a metabolically stable synthetic analog of prostaglandin F2α. Carboprost stimulates uterine contractions and induces abortion. Carboprost is used for postpartum hemorrhage due to uterine atony and for the termination of pregnancy in the second trimester [2].
Cat. No.: HY-121314
CAS No.: 40665-92-7
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Cloprostenol is a prostaglandin F-2α (PGF2α (HY-12956)) analogue. Cloprostenol induces luteolysis in marmoset monkeys. Cloprostenol can be used for the research of open-cervix pyometra [2].
Cat. No.: HY-101438
CAS No.: 139226-28-1
Synonyms: CI-1004
Research Areas:
Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50= 0.19 μM) but is much less potent with PGHS-1 (IC50=20 μM).
Synonyms: D-Cloprostenol
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(+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.
Synonyms: 8-iso-pgf2α
Target:
Cat. No.: HY-129953
CAS No.: 38432-87-0
Synonyms: 9α,11β-pgf2α
Category:
Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-125774
CAS No.: 38344-08-0
Synonyms: 17-Phenyl trinor pgf2α
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Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor .
Synonyms: 13,14-Dihydro-15-keto-pgf2α
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17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma [2].
Cat. No.: HY-125150
CAS No.: 64603-03-8
Synonyms: 11-Deoxy-16-fluoro pgf2α
Cat. No.: HY-125774S
CAS No.: 58976-50-4
Synonyms: 17-Phenyl trinor pgf2α-d4
Cat. No.: HY-113209S
CAS No.: 211105-40-7
Synonyms: 8-iso-pgf2α-d4
Cat. No.: HY-178792
CAS No.: 3073601-32-5
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TGI-15 is a highly selective prostaglandin F receptor antagonist. TGI-15 inhibits downstream signaling pathways by blocking the binding of PGF2 α to FP receptors. TGI-15 can be used for research on fibrotic and inflammatory conditions .
Cat. No.: HY-118816
CAS No.: 714966-38-8
Synonyms: 11-epi pgf2α-EA; 11β-pgf2α-EA; 11β-Prostamide F2α
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11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
