139226-28-1
139226-28-1
Chemical Structure
Darbufelone
Synonym(s): CI-1004
- CAS No.: 139226-28-1
- Formula:C18H24N2O2S
- Molecular Weight:332.46
IUPAC Name: (Z)-2-amino-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazol-4(5H)-one
InChIKey: AKTXOQVMWSFEBQ-LCYFTJDESA-N
SMILES: O=C1N=C(N)S/C1=C\C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Biological Activity: Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50= 0.19 μM) but is much less potent with PGHS-1 (IC50=20 μM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Darbufelone | 98.0% | Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50= 0.19 μM) but is much less potent with PGHS-1 (IC50=20 μM). | ||||||||||||||||||||
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Keywords
