714966-38-8
Chemical Structure
11β-Prostaglandin F2α
Synonym(s): 11-epi PGF2α-EA; 11β-PGF2α-EA; 11β-Prostamide F2α
- CAS No.: 714966-38-8
- Formula:C22H39NO5
- Molecular Weight:397.55
IUPAC Name: (Z)-7-((1R,2R,3S,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)-N-(2-hydroxyethyl)hept-5-enamide
InChIKey: XCVCLIRZZCGEMU-WMTHMIERSA-N
SMILES: OCCN(C(CCC/C=C\C[C@@H]1[C@H]([C@H](C[C@@H]1O)O)/C=C/[C@H](CCCCC)O)=O)[H]
Biological Activity: 11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
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11β-Prostaglandin F2α | 95.0% | 11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA. | ||||||||||||||||||||
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Keywords
