Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
piperidine derivative
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "piperidine derivative" in MCE Product Catalog:
Cat. No.: HY-W013154
CAS No.: 136030-33-6
Target:
Research Areas:
Fmoc-Tic-OH, an Fmoc-protected derivative of Tic, is a solid-phase peptide synthesis monomer. Fmoc-Tic-OH protects the amino group of Tic via a base-labile Fmoc group, allowing conformationally constrained Tic residues to be stepwise coupled to peptide chains, and the Fmoc protecting group can be removed under piperidine conditions. Fmoc-Tic-OH can be used for peptide synthesis and opioid receptor ligand research .
Research Areas:
N-piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51.0 and 30.7 nM for WT BTK and C481S BTK, respectively . N-piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM .
Cat. No.: HY-W694291
CAS No.: 15302-10-0
Target:
Research Areas:
Clibucaine is a piperidine derivative possessing local agent that can suppress or relieve pain. Clibucaine can be used as a local agent that can suppress or relieve pain .
Cat. No.: HY-135670A
CAS No.: 176485-27-1
Target:
Research Areas:
β-glycosidase-IN-1 (Compound 33) is a piperidine derivative and a β-glycosidase inhibitor. β-glycosidase-IN-1 has hypoglycemic activity .
Cat. No.: HY-144675
CAS No.: 2170212-33-4
Target:
Research Areas:
LSD1-IN-13 (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 induces differentiation of AML (acute myeloid leukemia) cell lines .
Cat. No.: HY-144675A
CAS No.: 2170347-90-5
Target:
Research Areas:
LSD1-IN-13 hydrochloride (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 hydrochloride can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 hydrochloride induces differentiation of AML (acute myeloid leukemia) cell lines .
Cat. No.: HY-146123
CAS No.: 2691937-03-6
Target:
Research Areas:
ATX inhibitor 20 (compound 24) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.3 nM .
Cat. No.: HY-144673
CAS No.: 1228143-76-7
Target:
Research Areas:
LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively .
Cat. No.: HY-W595110
CAS No.: 2259851-38-0
Target:
Research Areas:
3-((4-(Piperidin-4-yl) phenyl) amino) piperidine-2,6-dione hydrochloride is a drug derivative .
Cat. No.: HY-43459
CAS No.: 1814897-92-1
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
