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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
polyubiquitin
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "polyubiquitin" in MCE Product Catalog:
Cat. No.: HY-176426
Target:
Research Areas:
Subquinocin is a tumor suppressor CYLD inhibitor that inhibits USP family deubiquitinases (DUBs) activity of CYLD with an IC50 of 30 μM. Subquinocin enhances the activation of NF-κB and IFN pathways by inhibiting CYLD. Subquinocin promotes RIG-I-mediated activation of IRF3/IRF7 in the interferon pathway. Subquinocin can be used for the research of cancer and neurodegenerative diseases .
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Research Areas:
UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia .
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Research Areas:
Ac-Phe-NH2 is a non-competitive inhibitor of polyubiquitin chain elongation at Ki value of 8 mM by destabilizing the active trimer .
Cat. No.: HY-P990493
Target:
Research Areas:
Cat. No.: HY-164951
CAS No.: 2223042-67-7
Target:
Research Areas:
C1-BCEA-Acm is a linker, that can be used for synthesis of polyubiquitin chains and ubiquitin-modified substrates .
Cat. No.: HY-P701839
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBC; Ubiquitin C; polyubiquitin‑C; Ubiquitin C Splice Variant; UBC Protein; HMG20
Cat. No.: HY-P705992
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBC; Ubiquitin C; polyubiquitin‑C; Ubiquitin C Splice Variant; UBC Protein; HMG20
Cat. No.: HY-P86479
Synonyms: UBB; polyubiquitin-B; UBC; polyubiquitin-C; RPS27A; UBA80; UBCEP1; Ubiquitin-40S ribosomal protein S27a; Ubiquitin carboxyl extension protein 80; UBA52; UBCEP2; Ubiquitin-60S ribosomal protein L40; CEP52; Ubiquitin A-52 residue ribosomal pr; Ubiquitin K48;
Cat. No.: HY-P87377
Synonyms: Epididymis secretory protein Li 50 antibody; FLJ25987 antibody; HEL S 50 antibody; MGC8385 antibody; polyubiquitin B antibody; RPS 27A antibody; RPS27A antibody; UBA 52 antibody; UBA 80 antibody; UBA52 antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
