278806-03-4
278806-03-4
Chemical Structure
UC-764864
- CAS No.: 278806-03-4
- Formula:C19H18N2OS
- Molecular Weight:322.42
InChIKey: OEFOUCPCKSVCJM-ZHACJKMWSA-N
SMILES: O=C(C1=CC=C(CC)C=C1)/C=C/SC2=NC3=C(N2)C=CC(C)=C3
Biological Activity: UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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UC-764864 | 99.89% | UC-764864 is a selective UBE2N inhibitor. UC-764864 covalently binds UBE2N catalytic Cys87, blocks ubiquitin-UBE2N thioester formation and polyubiquitin chain synthesis. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates, and induces cell apoptosis. UC-764864 can be used for the research of acute myeloid leukemia. | ||||||||||||||||||||
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References
Keywords
