13 Results for "

pp125FAK

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "pp125FAK" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P80460
Synonyms: FAK, FAK1, PTK2, Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FRNK, ppP1R71

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse

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Cat. No.: HY-P1189
CAS No.: 154303-05-6
Echistatin is a naturally derived RGD-containing snake venom peptide. Echistatin exhibits an IC50 of 0.6 nM against mouse αvβ3 integrin, and acts as an antagonist against αvβ3, αII3, α5β1 integrins, pp125 FAK and paxillin. Echistatin reduces the phosphorylation of pp125 FAK and paxillin, inhibits the autophosphorylation and kinase activity of pp125 FAK, and weakens its binding to pp60src and paxillin. Echistatin disrupts the actin cytoskeleton and focal adhesions, induces melanoma cell detachment from fibronectin, and regulates cell adhesion and motility. Echistatin inhibits osteoclast maturation and migration, bone resorption, platelet aggregation, bone loss, as well as adhesion and metastasis of Lewis lung cancer cells; it also increases the number of osteoclasts and bone coverage area in mice with secondary hyperparathyroidism. Echistatin can be used in research related to melanoma, lung cancer and secondary hyperparathyroidism .
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Cat. No.: HY-P1189A
Echistatin TFA is a naturally derived RGD-containing snake venom peptide. Echistatin TFA exhibits an IC50 of 0.6 nM against mouse αvβ3 integrin, and acts as an antagonist against αvβ3, αII3, α5β1 integrins, pp125 FAK and paxillin. Echistatin TFA reduces the phosphorylation of pp125 FAK and paxillin, inhibits the autophosphorylation and kinase activity of pp125 FAK, and weakens its binding to pp60src and paxillin. Echistatin TFA disrupts the actin cytoskeleton and focal adhesions, induces melanoma cell detachment from fibronectin, and regulates cell adhesion and motility. Echistatin TFA inhibits osteoclast maturation and migration, bone resorption, platelet aggregation, bone loss, as well as adhesion and metastasis of Lewis lung cancer cells; it also increases the number of osteoclasts and bone coverage area in mice with secondary hyperparathyroidism. Echistatin TFA can be used in research related to melanoma, lung cancer and secondary hyperparathyroidism .
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Cat. No.: HY-P701682
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PTK2; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; ppP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK
Species:  
Source:  
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Cat. No.: HY-P706087
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Focal adhesion kinase 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; ppP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK; FAK; FAK1
Species:  
Source:  
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Cat. No.: HY-RS11399
Research Areas:  

Others

PTK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PTK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P85584
Synonyms: FADK 1; FADK; FAK 1; FAK 1; FAK related non kinase polypeptide; FAK1; FAK1_HUMAN; Focal adhesion kinase 1; Focal adhesion kinase 1; Focal adhesion Kinase; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; FRNK; p125FAK; pp125FAK; pp125FAK; ppP1R71; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein Tyrosine Kinase Cytoplasmic; Protein Tyrosine Kinase Cytoplasmic; Protein-tyrosine kinase 2; PTK 2; PTK 2; PTK2; PTK2 protein tyrosine kinase 2; PTK2 protein tyrosine kinase 2.

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P86571
Synonyms: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; ppP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85157
Synonyms: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; ppP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Host:  

Mouse

Application:  

WB, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P80816
Synonyms: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; ppP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

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Cat. No.: HY-P80816A
Synonyms: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; ppP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

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Cat. No.: HY-P80125
Synonyms: FAK, FAK1, PTK2, Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FRNK, ppP1R71

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC, IP

Reactivity:  

Human, Mouse

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Cat. No.: HY-P87691
Synonyms: FAK, FAK1, PTK2, Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FRNK, ppP1R71

Host:  

Rabbit

Application:  

WB, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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