2 Results for "

primary human Tregs

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "primary human Tregs" in MCE Product Catalog:

Cat. No.: HY-159692
CAS No.: 2603457-08-3
Synonyms: IONIS-1063734
Target:  

FOXP

Research Areas:  

Cancer

AZD8701 (IONIS-1063734) is an antisense oligonucleotide targeting FOXP3 in regulatory T cells (Tregs), with a human IC50 of 65.2 nM. AZD8701 binds to intronic sites of all FOXP3 pre-mRNA isoforms and mediates dose-dependent FOXP3 knockdown via free uptake. AZD8701 can be used in cancer-related research .
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Cat. No.: HY-172930B
CAS No.: 2991023-13-1
Research Areas:  

Cancer

(R)-PVTX-405 is a IKZF2 molecular glue degrader with a DC50 of 4.1 nM. (R)-PVTX-405 is the (R)-enantiomer of PVTX-405 (HY-172930). PVTX-405 is an orally active IKZF2 molecular glue degrader that significantly inhibits MC38 tumor growth in mouse tumor xenograft models. (R)-PVTX-405 can be used in cancer-related research .
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