2991023-13-1
2991023-13-1
Chemical Structure
(R)-PVTX-405
- CAS No.: 2991023-13-1
- Formula:C30H31N5O4
- Molecular Weight:525.60
InChIKey: SITNTOVOBBQZJQ-RUZDIDTESA-N
SMILES: O=C1N(CC2=C1C=CC3=C2OCC34CCN(CC5=CC=CC(C(C=N6)=CN6C)=C5)CC4)[C@@H](C7=O)CCC(N7)=O
Biological Activity: (R)-PVTX-405 is a IKZF2 molecular glue degrader with a DC50 of 4.1 nM. (R)-PVTX-405 is the (R)-enantiomer of PVTX-405 (HY-172930). PVTX-405 is an orally active IKZF2 molecular glue degrader that significantly inhibits MC38 tumor growth in mouse tumor xenograft models. (R)-PVTX-405 can be used in cancer-related research[1].
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(R)-PVTX-405 | (R)-PVTX-405 is a IKZF2 molecular glue degrader with a DC50 of 4.1 nM. (R)-PVTX-405 is the (R)-enantiomer of PVTX-405 (HY-172930). PVTX-405 is an orally active IKZF2 molecular glue degrader that significantly inhibits MC38 tumor growth in mouse tumor xenograft models. (R)-PVTX-405 can be used in cancer-related research. | |||||||||||||||||||||
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References
Keywords
