4 Results for "

rat brain synaptic membrane

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "rat brain synaptic membrane" in MCE Product Catalog:

Cat. No.: HY-W015793
CAS No.: 3167-49-5
6-Aminonicotinic acid is an analog of Niacin (HY-B0143) and also a GABAA receptor agonist with a Ki value of 4.4 μM in rats. 6-Aminonicotinic acid binds to both native and recombinant GABAA receptors, is metabolized into non-functional pyridine nucleotide analogs to inhibit dehydrogenases, and suppresses the proliferation of T2 bacteriophages. 6-Aminonicotinic acid accumulates in specific bacterial cells in the form of pyridine nucleotide analog metabolites. 6-Aminonicotinic acid can be used in research related to neurological disorders such as anxiety, epilepsy and schizophrenia, and also serves as an intermediate in organic synthesis .
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Cat. No.: HY-100821
CAS No.: 111872-98-1
2,4-Dihydroxyphenylacetylasparagine is a potent and selective antagonist of glutamate. 2,4-Dihydroxyphenylacetylasparagine inhibits glutamate binding to rat brain synaptic membranes .
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Cat. No.: HY-P3057A
CAS No.: 75644-95-0
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

[Trp11]-Neurotensin is a neurotensin analog and neurotensin receptor agonist. The Tyr11 residue of neurotensin is replaced by L-Trp. [Trp11]-Neurotensin competes for neurotensin receptor binding sites, with an IC50 of 4.3 nM in rat brain synaptic membranes, and activates neurotensin receptor-mediated smooth muscle responses, with an EC50 of 1.7 nM in rat ileum, exhibiting significant species-dependent differences in receptor recognition. [Trp11]-Neurotensin can be used in studies related to neurotensin receptor pharmacology, gastrointestinal smooth muscle, and species-dependent receptor recognition .
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Cat. No.: HY-15129A
CAS No.: 73913-63-0
Synonyms: D-Serine O-phosphate; D-SOP
Research Areas:  

Neurological Disease

O-Phospho-D-serine (D-SOP) is the D-configurational enantiomer of O-Phospho-L-serine (HY-15129). O-Phospho-D-serine inhibits L-[ 3H]glutamate binding to APB-sensitive sites in rat brain synaptic plasma membranes, with a Ki of 303 μM. Compared with the L-configurational form, D-SOP does not significantly activate the tested mGluR at 1 mM, and it is mainly used in studies related to the stereoselectivity of phosphatidylserine and mGluR ligands .
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