3167-49-5
Chemical Structure
6-Aminonicotinic acid
- CAS No.: 3167-49-5
- Formula:C6H6N2O2
- Molecular Weight:138.13
IUPAC Name: 6-aminonicotinic acid
InChIKey: ZCIFWRHIEBXBOY-UHFFFAOYSA-N
SMILES: O=C(O)C1=CN=C(N)C=C1
Biological Activity: 6-Aminonicotinic acid is a GABAA receptor agonist with Ki value of 4.4 nM. 6-Aminonicotinic acid can be formed via electrocatalytic synthesis at silver cathodes. 6-Aminonicotinic acid has a variety of biological properties, such as protein synthesis inhibitor, vitamin B3 agonist, and modulating agent in chemotherapy[1][2].
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6-Aminonicotinic acid | 99.56% | 6-Aminonicotinic acid is a GABAA receptor agonist with Ki value of 4.4 nM. 6-Aminonicotinic acid can be formed via electrocatalytic synthesis at silver cathodes. 6-Aminonicotinic acid has a variety of biological properties, such as protein synthesis inhibitor, vitamin B3 agonist, and modulating agent in chemotherapy. | ||||||||||||||||||||
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- [1]. Petersen JG, et al. Synthesis and pharmacological evaluation of 6-aminonicotinic acid analogues as novel GABA(A) receptor agonists. Eur J Med Chem. 2014 Sep 12;84:404-16. [Content Brief]
- [2]. Armando Gennaro, et al., Electrocatalytic synthesis of 6-aminonicotinic acid at silver cathodes under mild conditions, Electrochemistry Communications, Volume 6, Issue 7, 2004.
Keywords