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Results for "

sALT629

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (1) Calcium Channel (1) Endothelin Receptor (1) GCGR (1) GLP Receptor (1) Isotope-Labeled Compounds (5) PI3K (1) Potassium Channel (1) Proteasome (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (1) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1925A

GO-203 TFA 2 Publications Verification	PI3K Reactive Oxygen Species (ROS) Apoptosis	Cancer
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .

HY-145632A

Pemvidutide TFA ALT-801 TFA	GLP Receptor GCGR	Metabolic Disease
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .

HY-179649

*sALT629*	Bacterial	Infection
sALT629 is an orally active antitubercular agent with potent intramacrophage activity (EC₅₀ = 1.5 μM). sALT629 shows broad-spectrum anti-Mycobacterium tuberculosis (Mtb) activities across four carbon sources, equipotent efficacy against drug-resistant Mtb, and activity against both slow-replicating and nonreplicating Mtb. sALT629 exhibits synergistic activity when combined with oxazolidinone drugs, such as Linezolid (HY-10394) and Sutezolid (HY-10392). sALT629 can be used for the research of tuberculosis .

HY-P6013A

wt hMLN TFA	Calcium Channel	Others
wt hMLN (TFA) is a microprotein that inhibits of SR Ca ²⁺ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-P10002A

EWFW-ACC TFA	Biochemical Assay Reagents	Others
EWFW-ACC TFA is a specific immunoproteasome substrate that can be used to study immunoproteasome function .

HY-P5201S1

VTSEGAGLQLQK-13C6,15N2 TFA	Isotope-Labeled Compounds	Others
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .

HY-P10003A

iso-VQA-ACC TFA	Proteasome	Others
iso-VQA-ACC TFA is a constitutive proteasome substrate .

HY-156341S1

LLIYYTSSLHSGVPSR-(Arg-13C6,15N4) TFA	Isotope-Labeled Compounds	Others
LLIYYTSSLHSGVPSR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-156345S1

LPFTFGQGTK-(Lys-13C6,15N2) TFA	Isotope-Labeled Compounds	Others
LPFTFGQGTK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-156344S1

GLEWVAEIR-(Arg-13C6,15N4) TFA	Isotope-Labeled Compounds	Others
GLEWVAEIR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-156343S1

SNNYATHYAESVK-(Lys-13C6,15N2) TFA	Isotope-Labeled Compounds	Others
SNNYATHYAESVK-(Lys- ¹³C₆, ¹⁵N₂) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-P1426A

AmmTX3 TFA	Potassium Channel	Neurological Disease
AmmTX3 TFA is a peptide toxin identified from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is a highly specific blocker of K_v4 channels, which selectively and almost completely blocks transient A-type K ⁺ currents with a K_i of 131 nM. AmmTX3 TFA induces epileptiform behaviors and causes death in mice receiving intracerebroventricular injection. AmmTX3 TFA increases the excitability of dentate gyrus granule cells, reduces GABAergic inhibition, enhances and stabilizes the EPSP-spike component of long-term potentiation, and impairs reference memory. AmmTX3 TFA can be used in research related to pain, epilepsy, and autism spectrum disorder .

Cat. No.	Product Name	Target	Research Area

HY-P1925A

GO-203 TFA 2 Publications Verification	PI3K Reactive Oxygen Species (ROS) Apoptosis	Cancer
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .

HY-145632A

Pemvidutide TFA ALT-801 TFA	GLP Receptor GCGR	Metabolic Disease
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .

HY-P2512A

Phytochelatin 2 (PC2) TFA	Peptides	Others
Phytochelatin 2 (PC2) TFA is a phytochelatin, an important heavy metal-binding peptide. Phytochelatin 2 (PC2) TFA can chelate metals, prevent metal toxicity, and maintain metal stability in the internal environment .

HY-P6013A

wt hMLN TFA	Calcium Channel	Others
wt hMLN (TFA) is a microprotein that inhibits of SR Ca ²⁺ pump (SERCA). wt hMLN plays an important role in skeletal muscle calcium homeostasis .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-P10002A

EWFW-ACC TFA	Biochemical Assay Reagents	Others
EWFW-ACC TFA is a specific immunoproteasome substrate that can be used to study immunoproteasome function .

HY-P5201S1

VTSEGAGLQLQK-13C6,15N2 TFA	Isotope-Labeled Compounds	Others
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .

HY-P10003A

iso-VQA-ACC TFA	Proteasome	Others
iso-VQA-ACC TFA is a constitutive proteasome substrate .

HY-156341S1

LLIYYTSSLHSGVPSR-(Arg-13C6,15N4) TFA	Isotope-Labeled Compounds	Others
LLIYYTSSLHSGVPSR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-156345S1

LPFTFGQGTK-(Lys-13C6,15N2) TFA	Isotope-Labeled Compounds	Others
LPFTFGQGTK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-156344S1

GLEWVAEIR-(Arg-13C6,15N4) TFA	Isotope-Labeled Compounds	Others
GLEWVAEIR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-156343S1

SNNYATHYAESVK-(Lys-13C6,15N2) TFA	Isotope-Labeled Compounds	Others
SNNYATHYAESVK-(Lys- ¹³C₆, ¹⁵N₂) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-P1426A

AmmTX3 TFA	Potassium Channel	Neurological Disease
AmmTX3 TFA is a peptide toxin identified from the venom of the scorpion Androctonus mauretanicus. AmmTX3 TFA is a highly specific blocker of K_v4 channels, which selectively and almost completely blocks transient A-type K ⁺ currents with a K_i of 131 nM. AmmTX3 TFA induces epileptiform behaviors and causes death in mice receiving intracerebroventricular injection. AmmTX3 TFA increases the excitability of dentate gyrus granule cells, reduces GABAergic inhibition, enhances and stabilizes the EPSP-spike component of long-term potentiation, and impairs reference memory. AmmTX3 TFA can be used in research related to pain, epilepsy, and autism spectrum disorder .

Cat. No.	Product Name	Chemical Structure

HY-P5201S1

VTSEGAGLQLQK-13C6,15N2 TFA
VTSEGAGLQLQK-13C6,15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .

HY-156341S1

LLIYYTSSLHSGVPSR-(Arg-13C6,15N4) TFA
LLIYYTSSLHSGVPSR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-156345S1

LPFTFGQGTK-(Lys-13C6,15N2) TFA
LPFTFGQGTK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-156344S1

GLEWVAEIR-(Arg-13C6,15N4) TFA
GLEWVAEIR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-156343S1

SNNYATHYAESVK-(Lys-13C6,15N2) TFA
SNNYATHYAESVK-(Lys- ¹³C₆, ¹⁵N₂) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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