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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
serum response factor
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "serum response factor" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P4744
CAS No.: 597562-32-8
2
2 Cited Publications
Target:
Research Areas:
CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF .
2
2 Cited Publications
Cat. No.: HY-P4744A
MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis .
Cat. No.: HY-141439
CAS No.: 936475-62-6
Research Areas:
TBE 31 is an orally active Keap1/Nrf2 pathway activator and NQO1 inducer with a Dm value of 1.1 nM for NQO1. TBE 31 binds to cysteine residues of Keap1, inhibits ubiquitination and degradation of Nrf2, thereby activating the expression of ARE-dependent genes. TBE 31 induces cytoprotective enzymes including NQO1 and GST isoforms, promotes Nrf2 accumulation, and upregulates Nrf2-regulated genes related to antioxidation and lipid metabolism. TBE 31 inhibits pro-inflammatory responses, formation of AFB1-DNA adducts, endoplasmic reticulum stress, cell apoptosis (apoptosis), hepatic fibrosis, oxidative stress, and the expression of ChREBP. TBE 31 reduces the number of tumors in a mouse model of ultraviolet-induced skin carcinogenesis. TBE 31 enhances nerve growth factor-induced neurite outgrowth. TBE 31 attenuates LPS-induced serum TNF-α levels and immobility time in mice. TBE 31 can be used in research related to liver cancer, skin cancer, inflammation-related depression, and non-alcoholic steatohepatitis .
Cat. No.: HY-121490
CAS No.: 218929-99-8
IMM-02 is a DID-DAD binding inhibitor with activity promoting actin assembly and microtubule stabilization. IMM-02 is able to trigger serum response factor-mediated gene expression and lead to cell cycle arrest and apoptosis. IMM-02 has shown the ability to slow tumor growth in a mouse colon cancer xenograft model .
Cat. No.: HY-176466
CAS No.: 143484-41-7
Research Areas:
ST-899 is a novel platelet-activating factor (PAF) receptor antagonist. ST-899 can significantly reduce the mortality of mice with endotoxin (LPS)-induced shock. ST-899 can significantly inhibit the increase in serum tumor necrosis factor (TNF) levels induced by LPS, but has no effect on interleukin-6 (IL-6). The regulatory mechanism of ST-899 is to block the positive feedback loop between PAF and TNF, thereby reducing the inflammatory response. ST-899 can be used to study inflammatory diseases such as septic shock .
Cat. No.: HY-P87085
Synonyms: c fos serum response element binding factor antibody; c fos serum response element binding transcription factor antibody; ELK3 antibody; ERP antibody; MCM 1 antibody; MCM1 antibody; OTTHUMP00000039820 antibody; SAP2 antibody; serum response factor antibody; SRF antibody; c fos serum response element binding factor antibody; c fos serum response element binding transcription factor antibody; ELK3 antibody; ERP antibody; MCM 1 antibody; MCM1 antibody; OTTHUMP00000039820 antibody; SAP2 antibody; serum response factor antibody; SRF antibody; SRF serum response factor c fos serum response element binding transcription factor antibody; SRF_HUMAN antibody;
Cat. No.: HY-P77215
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: serum response factor-binding protein 1; p49/STRAP; SRFBP1
Species:
Source:
Cat. No.: HY-P81410A
Synonyms: MEF2B; XMEF2; Myocyte-specific enhancer factor 2B; RSRFR2; serum response factor-like protein 2
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
