3 Results for "

tactile hypersensitivity

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "tactile hypersensitivity" in MCE Product Catalog:

Cat. No.: HY-110099
CAS No.: 473722-68-8
Target:  

CXCR

Research Areas:  

Inflammation/Immunology

(±)-NBI-74330 is a potent and selective CXCR3 antagonist. (±)-NBI-74330 not only reduces tactile and thermal hypersensitivity but also enhances the analgesic properties of morphine. (±)-NBI-74330 can reduce microglial cell activation, increase astroglial cell activation, and downregulate the expression of some CXCR3 ligands in a rat neuropathic pain model .
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Cat. No.: HY-P10767
CAS No.: 2468971-42-6
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

MD01-67 is a selective macrocyclic compound targeting the neurotensin receptor type 2 (NTS2), with Ki of 2.9 nM. MD01-67 exhibits analgesic and tactile hypersensitivity reducing activity in rats acute/persistent/chronic inflammatory pain models .
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Cat. No.: HY-168333
CAS No.: 2727088-38-0
Target:  

5-HT Receptor mTOR CDK

Research Areas:  

Neurological Disease

5-HT6 inverse agonist 1 (Compound 33) is an antagonist for 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. 5-HT6 inverse agonist 1 inhibits the 5-HT6R mediated Cdk5 and mTOR signaling pathway. 5-HT6 inverse agonist 1 reduces tactile hypersensitivity in spinal nerve ligation (SNL)-induced rat model .
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