2468971-42-6
2468971-42-6
Chemical Structure
MD01-67
- CAS No.: 2468971-42-6
- Formula:C37H58N8O8
- Molecular Weight:742.91
InChIKey: NMDINTPQFLERGW-MMXDLGESSA-N
SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H]2NC([C@@H](NC([C@@H](NC([C@H](C/C=C/C2)N)=O)CCCCN)=O)CCCCN)=O)=O)C(N[C@H](C(O)=O)CC3CCCC3)=O
Biological Activity: MD01-67 is a selective macrocyclic compound targeting the neurotensin receptor type 2 (NTS2), with Ki of 2.9 nM. MD01-67 exhibits analgesic and tactile hypersensitivity reducing activity in rats acute/persistent/chronic inflammatory pain models[1].
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MD01-67 | MD01-67 is a selective macrocyclic compound targeting the neurotensin receptor type 2 (NTS2), with Ki of 2.9 nM. MD01-67 exhibits analgesic and tactile hypersensitivity reducing activity in rats acute/persistent/chronic inflammatory pain models. | |||||||||||||||||||||
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References
Keywords
