5-HT6 inverse agonist 1
5-HT6 inverse agonist 1 (Compound 33) is an antagonist for 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. 5-HT6 inverse agonist 1 inhibits the 5-HT6R mediated Cdk5 and mTOR signaling pathway. 5-HT6 inverse agonist 1 reduces tactile hypersensitivity in spinal nerve ligation (SNL)-induced rat model.
For research use only. We do not sell to patients.
- CAS No.: 2727088-38-0
- Formula: C22H22Cl2FN3O3S
- Molecular Weight:498.40
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All 5-HT Receptor Isoforms
More
Biological Activity
|
5-HT6 Receptor 23 nM (Ki) |
5-HT7 Receptor 1.85 μM (Ki) |
5-HT1A Receptor 72.42 μM (Ki) |
5-HT2A Receptor 98.51 μM (Ki) |
Chemical Information
-
CAS No. 2727088-38-0
-
Molecular Weight 498.40
-
Formula C22H22Cl2FN3O3S
-
SMILES
O=C(NC1CCNCC1)C2=C(N(C=C2)S(=O)(C3=CC=CC(Cl)=C3)=O)C4=CC=C(C=C4)F.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-HT6 inverse agonist 1 Related Classifications
HY-168333 Related Classifications
Powered by Bioz