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Results for "

triple helices

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-403689
    Fmoc-PNA-J(Boc)-OH

    		Biochemical Assay Reagents Others
    Fmoc-PNA-J(Boc)-OH is a nucleobase-modified PNA monomer (2-aminopyridine PNA monomer M) with Fmoc and Boc protecting groups, used for solid-phase synthesis of PNAs that form stable Hoogsteen triple helices with double-stranded RNA at physiologically relevant conditions .
    Fmoc-PNA-J(Boc)-OH
  • HY-131920
    Poly(U)

    Polyuridylic acid

    		 Toll-like Receptor (TLR) Inflammation/Immunology
    Poly (U) (Polyuridylic acid) is an RNA chain that exists in a disordered extended state at room temperature and serves as a TLR7 ligand. Poly (U) produces distinguishable blocking effects when transported through α-hemolysin nanopores. Poly (U) forms a triple helix with adenosine or adenosine monophosphate, thereby significantly promoting the nucleotide bond condensation reaction between adenosine monophosphate and adenosine, while exerting minimal effects on other nucleosides. When conjugated with cationic lipids, Poly (U) specifically stimulates plasmacytoid dendritic cells to produce type I interferons .
    Poly(U)

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