6912-67-0
Chemical Structure
Hydroxyproline
Synonym(s): DL-Hydroxyproline
- CAS No.: 6912-67-0
- Formula:C5H9NO3
- Molecular Weight:131.13
IUPAC Name: 4-hydroxypyrrolidine-2-carboxylic acid
InChIKey: PMMYEEVYMWASQN-UHFFFAOYSA-N
SMILES: O=C(C1NCC(C1)O)O
Biological Activity: Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagenous tissues. Hydroxyproline acts as a substrate for mitochondrial hydroxyproline oxidase to generate ROS. Hydroxyproline promotes the synthesis of glutathione, DNA, heme and proteins via conversion to Glycine (HY-Y0966). Hydroxyproline promotes the activation of caspase-9 and apoptosis in cancer cells treated with Doxorubicin. Hydroxyproline serves as a biochemical marker. Hydroxyproline is used in research related to various diseases including colon cancer, diabetes and arthritis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hydroxyproline | 98.0% | Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagenous tissues. Hydroxyproline acts as a substrate for mitochondrial hydroxyproline oxidase to generate ROS. Hydroxyproline promotes the synthesis of glutathione, DNA, heme and proteins via conversion to Glycine (HY-Y0966). Hydroxyproline promotes the activation of caspase-9 and apoptosis in cancer cells treated with Doxorubicin. Hydroxyproline serves as a biochemical marker. Hydroxyproline is used in research related to various diseases including colon cancer, diabetes and arthritis. | ||||||||||||||||||||
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References
- [1]. Wu Z, et al. Metabolism, Nutrition, and Redox Signaling of Hydroxyproline. Antioxidants & redox signaling. 2019 Feb 01;30(4):674-682. [Content Brief]
- [2]. Srivastava AK, et al. Hydroxyproline: A Potential Biochemical Marker and Its Role in the Pathogenesis of Different Diseases. Current protein & peptide science. 2016;17(6):596-602. [Content Brief]
