2-Methylbenzaldehyde
Based on 1 Customer Validation
2-Methylbenzaldehyde is an acaricide found in Morinda officinalis. 2-Methylbenzaldehyde exerts fumigant and contact acaricidal activity against Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Haemaphysalis longicornis. 2-Methylbenzaldehyde can be used for the research of severe fever with thrombocytopenia syndrome.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 529-20-4
- Formula: C8H8O
- Molecular Weight:120.15
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2-Methylbenzaldehyde (24 h) potently exerts fumigant acaricidal activity against D. farinae (LD50 = 0.95 μg/cm3), D. pteronyssinus (LD50 = 0.87 μg/cm3), and H. longicornis (LD50 = 1.28 μg/cm3)[1].
2-Methylbenzaldehyde (24 h) potently exerts contact acaricidal activity against D. farinae (LD50 = 0.51 μg/cm2), D. pteronyssinus (LD50 = 0.47 μg/cm2), and H. longicornis (LD50 = 0.94 μg/cm2)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 529-20-4
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Appearance Liquid (Density: 1.039 g/cm3)
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Molecular Weight 120.15
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Formula C8H8O
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Color Colorless to light yellow
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SMILES
O=CC1=CC=CC=C1C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (832.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (20.81 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (20.81 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (299 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.3229 mL | 41.6146 mL | 83.2293 mL | 208.0732 mL |
| 5 mM | 1.6646 mL | 8.3229 mL | 16.6459 mL | 41.6146 mL | |
| 10 mM | 0.8323 mL | 4.1615 mL | 8.3229 mL | 20.8073 mL | |
| 15 mM | 0.5549 mL | 2.7743 mL | 5.5486 mL | 13.8715 mL | |
| 20 mM | 0.4161 mL | 2.0807 mL | 4.1615 mL | 10.4037 mL | |
| 25 mM | 0.3329 mL | 1.6646 mL | 3.3292 mL | 8.3229 mL | |
| 30 mM | 0.2774 mL | 1.3872 mL | 2.7743 mL | 6.9358 mL | |
| 40 mM | 0.2081 mL | 1.0404 mL | 2.0807 mL | 5.2018 mL | |
| 50 mM | 0.1665 mL | 0.8323 mL | 1.6646 mL | 4.1615 mL | |
| 60 mM | 0.1387 mL | 0.6936 mL | 1.3872 mL | 3.4679 mL | |
| 80 mM | 0.1040 mL | 0.5202 mL | 1.0404 mL | 2.6009 mL | |
| 100 mM | 0.0832 mL | 0.4161 mL | 0.8323 mL | 2.0807 mL |
2-Methylbenzaldehyde Related Classifications
HY-Y0442 Related Classifications
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