Sulfinalol

Art. -Nr.: HY-106499: Data Sheet Handling Instructions
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Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity.

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Sulfinalol Chemische Struktur

CAS. Nr. : 66264-77-5

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This product is a controlled substance and not for sale in your territory.

Other Forms of Sulfinalol:

Sulfinalol hydrochloride Angebot einholen

Spezialitätsempfehlungen

•Related Small Molecules:

•Related Proteins:

Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

α adrenergic receptor β adrenergic receptor

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung

Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity^[1].

IC₅₀ & Target

β-adrenoceptor

In Vivo

Sulfinalol shows direct vasodilator activity and antihypertensive activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)^[1]
Dosage:	0-100 µg
Administration:	Intraarterial injection
Result:	Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs.

Animal Model:	Male spontaneously hypertensive rats (SHR)^[1]
Dosage:	2.5 mg/kg
Administration:	Oral administration
Result:	Reduced pressure of conscious spontaneously hypertensive rats.

Molekulargewicht

377.50

Formel

C₂₀H₂₇NO₄S

CAS. Nr.

66264-77-5

SMILES

COC(C=C1)=CC=C1CCC(C)NCC(C2=CC(S(C)=O)=C(O)C=C2)O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. E J Sybertz, et al. Studies on the mechanism of the acute antihypertensive and vasodilator actions of several beta-adrenoceptor antagonists. J Cardiovasc Pharmacol. 1982 Sep-Oct;4(5):749-58. [Content Brief]

Sulfinalol Related Classifications

Cardiovascular Disease

Molaritätsrechner
Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Diese Gleichung wird häufig abgekürzt als: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfinalol66264-77-5Adrenergic ReceptorBeta ReceptorVasodilator activityOrally activeInhibitorinhibitorinhibit

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