DBCO-PEG4-VA-PBD
Based on 1 Customer Validation
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 2241644-09-5
- Formula: C80H87N9O16
- Molecular Weight:1430.60
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Storage:
-80°C, stored under nitrogen
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
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Traditional Cytotoxic Agents |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2241644-09-5
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Appearance Solid
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Molecular Weight 1430.60
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Formula C80H87N9O16
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Color White to light yellow
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SMILES
[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N9C%10=CC=CC=C%10C#CC%11=CC=CC=C%11C9)=O)=O)=O)=O)=O)C=C8)C1
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Shipping
Shipping with dry ice.
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Storage
-80°C, stored under nitrogen
Solvent & Solubility
DMSO : ≥ 100 mg/mL (69.90 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6990 mL | 3.4950 mL | 6.9901 mL | 17.4752 mL |
| 5 mM | 0.1398 mL | 0.6990 mL | 1.3980 mL | 3.4950 mL | |
| 10 mM | 0.0699 mL | 0.3495 mL | 0.6990 mL | 1.7475 mL | |
| 15 mM | 0.0466 mL | 0.2330 mL | 0.4660 mL | 1.1650 mL | |
| 20 mM | 0.0350 mL | 0.1748 mL | 0.3495 mL | 0.8738 mL | |
| 25 mM | 0.0280 mL | 0.1398 mL | 0.2796 mL | 0.6990 mL | |
| 30 mM | 0.0233 mL | 0.1165 mL | 0.2330 mL | 0.5825 mL | |
| 40 mM | 0.0175 mL | 0.0874 mL | 0.1748 mL | 0.4369 mL | |
| 50 mM | 0.0140 mL | 0.0699 mL | 0.1398 mL | 0.3495 mL | |
| 60 mM | 0.0117 mL | 0.0583 mL | 0.1165 mL | 0.2913 mL |
DBCO-PEG4-VA-PBD Related Classifications
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