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Cat. No.: HY-114950R

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EXP3179 (Standard)

(Synonyms: Losartan Carboxaldehyde (Standard); DuP 167 (Standard))

EXP3179 (Standard) is the analytical standard of EXP3179. This product is intended for research and analytical applications. EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions.

For research use only. We do not sell to patients.

CAS No.: 114798-36-6
Formula: C₂₂H₂₁ClN₆O
Molecular Weight:420.89

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

EXP3179 (Standard) Chemical Structure

CAS No.: 114798-36-6

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Fluorescent Dye

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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 114798-36-6
Molecular Weight 420.89
Formula C₂₂H₂₁ClN₆O
SMILES

[H]N1N=NN=C1C2=CC=CC=C2C3=CC=C(C=C3)CN4C(C([H])=O)=C(N=C4CCCC)Cl
Synonyms

Losartan Carboxaldehyde (Standard); DuP 167 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Rossi GP. Losartan metabolite EXP3179: an AT1-receptor-independent treatment strategy for patients with the metabolic syndrome?. Hypertension. 2009;54(4):710-712. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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