114798-36-6
Chemical Structure
EXP3179
Synonym(s): Losartan Carboxaldehyde; DuP 167
- CAS No.: 114798-36-6
- Formula:C22H21ClN6O
- Molecular Weight:420.89
IUPAC Name: 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde
InChIKey: FQZSMTSTFMNWQF-UHFFFAOYSA-N
SMILES: [H]N1N=NN=C1C2=CC=CC=C2C3=CC=C(C=C3)CN4C(C([H])=O)=C(N=C4CCCC)Cl
Biological Activity: EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions[1].
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EXP3179 | 98.09% | EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions. | ||||||||||||||||||||
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EXP3179 (Standard) | ≥98% | EXP3179 (Standard) is the analytical standard of EXP3179. This product is intended for research and analytical applications. EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions. | ||||||||||||||||||||
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Keywords
