IL17C - interleukin 17C Gene

Also Known as CX2; IL-17C

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27189

About IL17C

Cytogenetic location: 16q24.2 Genomic coordinates (GRCh38): 16:88,638,572-88,640,468 (from NCBI)

This gene has 2 transcripts (splice variants), 186 orthologues and 5 paralogues. Biased expression in endometrium (RPKM 1.7), gall bladder (RPKM 0.2) and 1 other tissue.

Summary

The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008]

IL17C Products (1)

mRNA Protein Name
NM_013278.4 NP_037410.1 interleukin-17C precursor

IL17C Protein Structure

IL17

IL17: Interleukin-17 (103 - 192)

  • 0
  • 100
  • 197 a.a.
Protein Preferred Names Protein Names

interleukin-17C

  • cytokine CX2

Recombinant IL17C Proteins

Cat. No. Product Name Accession Purity
HY-P72383 IL-17C Protein, Human (Biotinylated, HEK293, His-Avi) Q9P0M4 (H19-V197) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P72587 IL-17C Protein, Human (HEK293, His) Q9P0M4 (H19-V197) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P75836 IL-17C Protein, Human (sf9, Fc) Q9P0M4 (H19-V197) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P78469 IL-17C Protein, Human (HEK293, His-Avi) Q9P0M4 (H19-V197) ≥ 95%, as determined by Bis-Tris PAGE.

Related Diseases

Diseases Alias
Anal Gland Neoplasm

  • Anal Gland Neoplasms
Cutaneous Candidiasis

  • Candidiasis, Cutaneous
Non-Syndromic X-Linked Intellectual Disability 89

  • Mrx89
Pustulosis Of Palm And Sole

  • Psoriasis

  • Acropustulosis

  • Palmoplantar Pustulosis

  • Pustular Psoriasis Of The Palms And/Or Soles

  • Pustulosis Of Palms And Soles

  • Acrodermatitis Continua Of Hallopeau

  • Generalized Pustular Psoriasis
Septal Myocardial Infarction
Mental Retardation, X-Linked 92

  • MRX92

  • Intellectual Developmental Disorder, X-Linked 92

  • Non-Syndromic X-Linked Intellectual Disability 92

  • X-Linked Mental Retardation 92

  • Mental Retardation, X-Linked, Type 92
Chlorhexidine Allergy
Autoimmune Disease Of Skin And Connective Tissue
Chronic Mucocutaneous Candidiasis

  • Candidiasis, Chronic Mucocutaneous

  • Cmc

  • Candidiasis Chronic Mucocutaneous
Systemic Lupus Erythematosus

  • Lupus Nephritis

  • SLE

  • Disseminated Lupus Erythematosus

  • Systemic Lupus Erythematosus, Susceptibility To

  • Lupus Erythematosus, Systemic

  • Lupus Nephritis, Susceptibility To

  • Libman-Sacks Disease

  • Systemic Lupus Erythematosus Susceptibility To

  • Sle - Lupus Erythematosus, Systemic

  • Le Syndrome

  • Lupus

  • Lupus Erythematosus Systemic

  • Lupus Erythematosus, Systemic, Susceptibility To

  • Lupus Vulgaris

  • Lupus Erythematosus, Discoid

  • Lupus Erythematosus

  • Systemic Lupus Erythematosus Nos

  • Sle - [Systemic Lupus Erythematosus]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991598 MOR-106 Inhibitor 97.42% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P5963 Lib2-1 Inhibitor 99.63% Unkown
HY-RS06699 IL17C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19014 Il17c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25503 Il17c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IL17C RGD RGD:1582798
Mus musculus IL17C MGD MGI:2446486
Bos taurus IL17C VGNC VGNC:30119
Canis familiaris IL17C VGNC VGNC:41944
Others IL17C NCBI