SSX7 - SSX family member 7 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 280658

About SSX7

Cytogenetic location: Xp11.22 Genomic coordinates (GRCh38): X:52,644,061-52,654,900 (from NCBI)

This gene has 1 transcript (splice variant), 104 orthologues and 7 paralogues. Low expression observed in reference dataset.

Summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in Cancer patients, and are potentially useful targets in Cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]

SSX7 Products (1)

mRNA Protein Name
NM_173358.2 NP_775494.1 protein SSX7

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SSX7 Protein Structure

SSXRD

SSXRD: SSXRD motif (155 - 188)

  • 0
  • 100
  • 188 a.a.
Protein Preferred Names Protein Names

protein SSX7

  • synovial sarcoma, X breakpoint 7

SSX7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SSX7 Q7RTT5 LRRC45 Homo sapiens Q96CN5
Validated Y2H
32296183
Intra
SSX7 Q7RTT5 LRRC45 Homo sapiens Q96CN5
Y2H Prey Pooling
32296183
Intra
SSX7 Q7RTT5 CIB1 Homo sapiens Q99828
Validated Y2H
32296183
Intra
SSX7 Q7RTT5 CIB1 Homo sapiens Q99828
Y2H Array
32296183
Intra
SSX7 Q7RTT5 CIB1 Homo sapiens Q99828
Y2H Prey Pooling
32296183
Intra
SSX7 Q7RTT5 SERTAD1 Homo sapiens Q9UHV2
Y2H Prey Pooling
32296183
Intra
SSX7 Q7RTT5 SERTAD1 Homo sapiens Q9UHV2
Validated Y2H
32296183
Intra
SSX7 Q7RTT5 DNAAF11 Homo sapiens Q86X45
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13842 SSX7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown