LRRC45 - leucine rich repeat containing 45 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 201255

Summary

Involved in cilium assembly and protein localization to centriolar satellite. Located in centriole; centrosome; and ciliary basal body. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in colon (RPKM 3.3), bone marrow (RPKM 3.0) and 25 other tissues.

LRRC45 Products (1)

mRNA Protein Name
NM_144999.4 NP_659436.1 leucine-rich repeat-containing protein 45

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
21399614 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRRC45 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LRRC45 Q96CN5 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
LRRC45 Q96CN5 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
LRRC45 Q96CN5 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
LRRC45 Q96CN5 CCDC89 Homo sapiens Q8N998
Y2H Prey Pooling
32296183
Intra
LRRC45 Q96CN5 CCDC89 Homo sapiens Q8N998
Y2H Array
32296183
Intra
LRRC45 Q96CN5 SSX7 Homo sapiens Q7RTT5
Y2H Array
32296183
Intra
LRRC45 Q96CN5 SSX2 Homo sapiens Q16385-2
Y2H Array
32296183
Intra
LRRC45 Q96CN5 SSX2 Homo sapiens Q16385-2
Y2H Prey Pooling
32296183
Intra
LRRC45 Q96CN5 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra
LRRC45 Q96CN5 MCC Homo sapiens P23508
Y2H Array
32296183
Intra
LRRC45 Q96CN5 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
32296183
Intra
LRRC45 Q96CN5 ALAS1 Homo sapiens P13196
Y2H Array
32296183
Intra
LRRC45 Q96CN5 KXD1 Homo sapiens Q9BQD3
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07808 LRRC15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17927 Lrrc15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07812 LRRC25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07818 LRRC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07819 LRRC41 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07820 LRRC47 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07821 LRRC4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07822 LRRC4C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07823 LRRC55 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18668 Lrrc4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20174 Lrrc4c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20564 Lrrc25 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24397 Lrrc15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25154 Lrrc4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26678 Lrrc4c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27073 Lrrc25 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown