5α-Dihydrodeoxycorticosterone
Based on 1 Customer Validation
5α-Dihydrodeoxycorticosterone is an intermediate product of Deoxycorticosterone (HY-113414) catalyzed by 5α-reductase. 5α-Dihydrodeoxycorticosteron levels associated with depression.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 298-36-2
- Formula: C21H32O3
- Molecular Weight:332.48
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 298-36-2
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Appearance Solid
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Molecular Weight 332.48
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Formula C21H32O3
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Color White to off-white
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SMILES
[H][C@@]12CC[C@]3(CC(CC[C@@]3([C@]1(CC[C@]4([C@]2(CC[C@@H]4C(CO)=O)[H])C)[H])C)=O)[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (300.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0077 mL | 15.0385 mL | 30.0770 mL | 75.1925 mL |
| 5 mM | 0.6015 mL | 3.0077 mL | 6.0154 mL | 15.0385 mL | |
| 10 mM | 0.3008 mL | 1.5038 mL | 3.0077 mL | 7.5192 mL | |
| 15 mM | 0.2005 mL | 1.0026 mL | 2.0051 mL | 5.0128 mL | |
| 20 mM | 0.1504 mL | 0.7519 mL | 1.5038 mL | 3.7596 mL | |
| 25 mM | 0.1203 mL | 0.6015 mL | 1.2031 mL | 3.0077 mL | |
| 30 mM | 0.1003 mL | 0.5013 mL | 1.0026 mL | 2.5064 mL | |
| 40 mM | 0.0752 mL | 0.3760 mL | 0.7519 mL | 1.8798 mL | |
| 50 mM | 0.0602 mL | 0.3008 mL | 0.6015 mL | 1.5038 mL | |
| 60 mM | 0.0501 mL | 0.2506 mL | 0.5013 mL | 1.2532 mL | |
| 80 mM | 0.0376 mL | 0.1880 mL | 0.3760 mL | 0.9399 mL | |
| 100 mM | 0.0301 mL | 0.1504 mL | 0.3008 mL | 0.7519 mL |