1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. 5α-Hydroxy-6-keto cholesterol

5α-Hydroxy-6-keto cholesterol 

Cat. No.: HY-123349
Handling Instructions

5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM.

For research use only. We do not sell to patients.

5α-Hydroxy-6-keto cholesterol Chemical Structure

5α-Hydroxy-6-keto cholesterol Chemical Structure

CAS No. : 13027-33-3

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Description

5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM[1].

In Vitro

5α-Hydroxy-6-keto cholesterol (0.01, 0.1, 1, 10 μM) is cytotoxic to cultured 16-HBE cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

418.65

Formula

C₂₇H₄₆O₃

CAS No.
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Product Name:
5α-Hydroxy-6-keto cholesterol
Cat. No.:
HY-123349
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